UbiquiTx is a stealth biotech company pioneering the next generation of targeted protein modulators. We are designing a novel class of therapeutics that potently and selectively modulate historically undruggable targets not currently addressable by small-molecule degraders utilizing computationally-designed protein fusions that can both bind to a target of interest and tag it for targeted intracellular modulation.

UbiquiTx is seeking a highly motivated, creative and solutions-oriented Associate Scientist to join its therapeutic discovery team located in Cambridge, MA. As a member of an interdisciplinary team, this individual will support key aspects of biological assays, pre-clinical studies, platform and research programs for the development of UbiquiTx’s programs and future pipeline product candidates. In this hands-on laboratory position, the successful candidate will contribute to the preclinical discovery, development and assessment of UbiquiTx’s novel platform. In particular, the applicant should have experience in mammalian cell culturing techniques, molecular biology, and in vitro assay development. The applicant is expected to have a robust experimental skill set, an eagerness for learning, and contribute to a strong culture of teamwork and collaboration in a fast-paced environment.

Primary responsibilities will include:

·       Maintain and passage mammalian cell lines, including routine health monitoring, mycoplasma testing, and cryopreservation

·       Execute cell-based assays including viability, and functional assays with consistency and attention to detail

·       Retroviral or lentiviral transduction of cell lines and expression validation; protein/antibody expression, qPCR, and flow cytometry

·       Help manage day-to-day lab operations including ordering supplies, maintaining equipment logs, managing inventory, and ensuring common areas and cell culture facilities are organized and compliant with safety standards

·       Assist with general lab maintenance including autoclave runs, waste disposal, and routine equipment maintenance and troubleshooting

·       Generate, analyze, and communicate data in a timely manner via scientific presentations or written reports

·       Follow experimental protocols accurately and help establishing SOPs 

·       Build and maintain relationships with vendors and assist with technical aspects of vendor communications

·       Actively contribute to a collaborative, team-oriented atmosphere and assist colleagues as needed

·       Maintain high standards of laboratory safety

Required Skills:

·       Hands-on experience in mammalian cell culture — candidates should be comfortable independently maintaining multiple cell lines in a fast-paced environment

• The applicant is expected to have an eagerness for learning, and contribute to a strong culture of teamwork and collaboration in a fast-paced environment

·       MS/BS in Biology with a minimum of 2 years relevant laboratory experience

·       Experience with in vitro cell-based assays

·       Ability to work independently and able to balance multiple tasks or projects

·       Ability to follow detailed protocols  

·       Strong organizational skills and attention to detail; diligent experimental record keeping using an ELN system

·       Ability to manage lab supplies and contribute to the operational upkeep of a shared research facility

·       Collaborative, reliable, and positive attitude; comfortable balancing multiple tasks in a dynamic environment

·       Collaborative, and proactive

Optional skills:

·       Experience with AAV or Lenti/retroviral transduction

·       Nucleic acid quantitation by qPCR

·       Flow cytometry sample preparation and data analysis

·       Experience with molecular cloning techniques and site-directed mutagenesis

UbiquiTx is proud to be an equal opportunity workplace and is an affirmative action employer.